Hodgkin lymphoma is a relatively rare disease with around 75 New Zealanders each year being diagnosed with this disease.
Hodgkin Lymphoma (formerly known as Hodgkin’s Disease) is cancer of the lymphatic system, part of the immune system, and mainly affects the lymphocytes. Hodgkin lymphoma differs from non-Hodgkin lymphoma as it is characterised by the presence of a particular cancer cell, known as the Reed-Sternberg cell.
Hodgkin lymphoma can be cured; this is especially true for younger patients who are diagnosed with early-stage disease. Advanced stage Hodgkin lymphoma can also be treated very successfully and cured in a high proportion of patients.
Lymphoma is often difficult to diagnose as the symptoms are similar to those of a virus.
Symptoms may include:
There is no known single, or specific, cause of lymphoma. The risk increases slightly in some patients with chronic infections, autoimmune diseases such as coeliac disease, or rheumatoid diseases such as rheumatoid arthritis. People who have received long courses of chemotherapy or radiation for other diseases may also have increased risk of lymphoma.
Immuno-deficiency or deficiency of the immune system which has been inherited, or caused by viruses such as the AIDS virus or Epstien-Barr virus, is also a risk factor in developing lymphoma. However, apart from highly-specialised circumstances, there is no specific infectious cause and there are no known substances that cause lymphoma.
If lymphoma is suspected a blood test will be carried out to check for any abnormalities. This test might indicate an underlying malignant (cancerous) blood disease. It also gives a blood cell count and is useful for providing information on the likely behaviour of the lymphoma as well as how the kidneys and liver are functioning.
Diagnosis is confirmed following a lymph-node biopsy. This involves removing a lymph node or sample tissue to be examined in the laboratory. This will determine whether lymphoma is present and whether it is low, intermediate or high grade. The lymphoma may occupy only one area in the body (stage 1) or it may have spread throughout the body (up to stage 4). The personâ€™s age, general medical condition and whether the lymphoma is low, intermediate or high grade will all have an affect on the prognosis. Staging is the final step in determining the appropriate treatment plan but often a second series of tests are carried out before this happens. Testing can take a number of forms and includes:
Some types of lymphoma grow very slowly and do not need treating for a long time, if at all. Treatment for each person is determined by factors such as age, general health, type of lymphoma and whether it has spread to other parts of the body.
The aim of treatment is to destroy as many cancerous cells as possible and bring the disease into remission. There are a number of treatments that can be used to do this, but the main ones are chemotherapy, radiation therapy or a stem cell transplant.
For more information on treatments visit here.